Stroker has had solo performances at the Kennedy Center in Washington, D.C., and New York's Town Hall in addition to concert performances at Lincoln Center in New York City.[7]

Stroker starred in the Paper Mill Playhouse's production of The 25th Annual Putnam County Spelling Bee. She later reprised her role in this show at Philadelphia Theatre Company, and that performance earned her a Barrymore Award nomination.[8]

In 2011 Stroker made an appearance in the short film I Was a Mermaid and Now I'm a Pop Star.[9] In 2012 she auditioned for The Glee Project and was cast for the 12-episode series. She made it to the final episode and placed second, earning a guest role on Glee, playing Betty Pillsbury, Ms. Pillsbury's niece, in Season 4, Episode 14: "I Do".

In 2014 she had a role in the film Cotton, also known as "Everyday Miracles". In 2014 and 2015 Stroker had a three-episode role playing Wendy in the MTV series Faking It.

In 2015 she made history by becoming the first actress who uses a wheelchair to appear on a Broadway stage. She originated the role of Anna in Deaf West Theatre's 2015 revival of Spring Awakening.[10]

In 2017 Stroker was cast as Tamara in the ABC show Ten Days in the Valley.[11]

In 2018 she played Ado Annie in St. Ann's Warehouse's critically acclaimed revival of Oklahoma![3] The production transferred to Broadway's Circle in the Square Theatre in 2019, earning Stroker a Tony Award for Best Featured Actress in a Musical, making her the first person with a disability to be nominated for and to receive that award.[12][13]

In 2020 she was in Lifetime's Christmas Ever After, airing on December 6, 2020.